This paper selects important indicators of economic development of Chengdu-Chongqing in recent years to compare with ones of Shanghai, Guangzhou and Beijing, using national economic development indicators as a reference, and sets up mathematical model with the aid of Location Quotient (LQ), then uses deviation index to do secondary quantitative research, and builds urban core competitive power evaluation criteria, summarizes the advantage and the core issues on economic developtment of Chengdu and Chongqing,finally, proposes five countermeasures on strengthening the core competitiveness of Chengdu-Chongqing, with addressing the core issues in perspective of the city material properties, spirit properties and city value.