The administrative regulation mechanism of Extended Producer Responsibility regime is one type of administrative regulation mechanism. It is a whole dynamic process of producers’ compulsorily assuming the legal extended responsibility by means of administrative regulation. The administrative regulation mechanism of Extended Producer Responsibility regime has the attribute of public law because national environmental regulation power is the base of the construction of the administrative regulation mechanism of Extended Producer Responsibility regime. To define the administrative regulation range of Extended Producer Responsibility regime is actually to define the producers to assume the legal extended responsibility. And to define the producers to assume the legal extended responsibility is actually to define the waste products which are applicable for the administrative regulation mechanism of Extended Producer Responsibility regime. The resources factor and the environment factor are the key factors to define the administrative regulation range of Extended Producer Responsibility regime. The installation and consummation of the supervision and sanction of the administrative regulation mechanism of Extended Producer Responsibility regime help the timely detection and correction of default and inappropriate behaviors of the producers. In order to effectively deal with the increasingly severe problem of waste products, not only the above-mentioned measures but also the measures of investigating and affixing the producer’s legal responsibility should be taken.