With spatial econometric model, this paper does research on related factors of Chongqing economic development since the “Western development”. The study shows that, inspection period, Chongqing region has obvious spatial clustering phenomena, and forms industry development clusters which have local characteristics; due to spatial geography environmental, the development of the first industrial is weak promoting effect on regional economic comprehensive ascension, the second and third industry also play a more significant role in promoting regional economic growth; in addition, human capital investment obviously accelerates regional economic development. So we think that, in order to promote the Chongqing area economically reasonable and sustainable development, besides continuing to increase the fixed assets investment, optimizing the upgrading of the industrial structure is the key.