Historical materialism is the scientific theory of social development.The developing process of socialism with Chinese characteristics is consistent with and the principles of historical materialism.The core values of Chinese socialism generally descript the substantive characteristics of socialism, and the Four-Pronged Comprehensive Strategy has been the strategic layout since 18th CPC National Congress.There are close relationships between the two.The article discussed the relationship between the Four-Pronged Comprehensive Strategy and the core values of Chinese socialism based on historical materialism, related theories including the theory of social organism, the theory of social basic contradiction, the activism theory of social consciousness and the mass history theory.The two coincide with each other well:the core values are reflected in the Four-Pronged Comprehensive Strategy, and the Four-Pronged Comprehensive Strategy indicates the connotation of the core values.