This paper uses the spatial Gini-coefficient and the location quotient to measure the agglomeration degree of science and technology service industry in Fujian province,and comprehensively examines agglomeration of science and technology service industry in Fujian province based on the global and local spatial autocorrelation analysis method,then divides it into high agglomeration area and low agglomeration area. The empirical research on the panel data of Fujian Province shows that the degree of tacit knowledge spillover,citysize,government behavior and FDI are the main influencing factors for the agglomeration development of science and technology service industry in Fujian province,and all the influencing factors show certain regional differences. For this reason,the paper puts forward the policy suggestion of differentiated "gradient cluster" according to the agglomeration status of science and technology service industry in Fujian province.