In the increasingly fierce international competition, the lack of a comprehensive understanding on national innovation system of standardization has restricted China's transformation from a large manufacturing country to a strong manufacturing country. On the basis of systematically combing the related documents of the manufacturing standardization innovation system of the United States, Germany, Japan and other countries with higher technological level, the article compares the five aspects of the innovation system:main institutions, main factors, synergy, protective mechanism and path. The main institutions mainly include governments, enterprises, educational institutions, intermediary platforms and standardization organizations; main factors focus on knowledge, talents, capital and infrastructure; synergy mainly analyzes and compares the linkage of various institutions and factors in the innovation system; the protection mechanism mainly discusses intellectual property rights and patent systems; the path emphasizes the path-dependent characteristics of the innovation systems of standardization of various countries, which cannot be copied, but can be used for reference to foster the advantages and strengths of the system. Through the literature analysis and comparison of these five aspects, prescriptive research method is adopted to originally explore the model of national innovation system of innovation-driven standardization in China. The model indicates four levels:the core, the micro, the middle, and the macro level. At the core level, it is important to accurately grasp the standardization and innovation collaboration of "knowledge-technology-patent-standard" path, in which knowledge is generated, absorbed, transferred, diffused, and integrated to new knowledge. At the micro level, it is necessary to strictly require standardization as the primary goal based on the link of "enterprise-education & training institution-scientific research institution-domestic standardization organization". The micro level plays a role in the generation, learning, research and development of standardization from the "point" level. At the middle level, it is necessary to actively promote the collaborative cooperation of "industry alliance-financial institution-intermediary agency-industry association". The meso level serves the integration of resources of standardization from the "line" level. At the macro level, it is necessary to focus on strengthening the "government-ISO" international exchanges and interactions, promoting the compatibility of Chinese standards and international standards from the "surface" level. Finally, for building a national innovation system for innovation-driven standardization of manufacturing enterprises, the article provides policy suggestions on six aspects including "government and market", "opening up", "platform building", "innovation effect", "standard internationalization" and "training mechanism".