In February 2022, the Guidelines on Deepening the Construction of World-class Universities and Disciplines were published, and the second list of universities and disciplines included in the Double First-class Project was released. Xi Jinping, General Secretary of the CPC Central Committee, has pointed out that "only those universities that cultivate first-class talents can become world-class universities. To run China’s universities successfully and turn them into world-class universities, we must firmly grasp the core point of comprehensively improving the ability to cultivate talents." Cultivating first-class talents is a key issue that cannot be avoided under the background of Double First-class construction. As the "pioneer" of the pilot reform of first-class talent training, Double First-class construction universities should firmly grasp the core point of comprehensively improving the ability of talent training, and give full play to the role of the main force in training urgently needed high-level talents and basic research talents. The proposal and evolution of the concept of Double First-class provides an important theoretical basis for the study of first-class talents. The major strategic deployment of talents of the CPC Central Committee in recent years and the objective needs of the talent-strengthening strategy have given strategic significance to the research of first-class talents. From the perspective of universities’ basic functions, improving the quality of talent training and cultivating first-class talents is the core mission of building first-class universities. First-class talents should have first-class knowledge and skills, have first-class innovation ability, and have an advanced sense of contributing to the country, society and the people. They are endowed with common characteristics such as high integrity, all-round development, love of country, broad vision, based on practice, and courage to innovate. To establish a scientific first-class talent evaluation scale, we must not only establish a correct value orientation, and reform the traditional "five-dimensions-only" assessment system, but also form a diversified evaluation system. It plays an important role in maximizing the innovation and creativity of talents and their potential. Under the background of Double First-class construction, the cultivation of first-class talents is not only a response to the national strategic needs, but also calls for the return of the authenticity of education and meets the needs of talent development. Therefore, we must deeply understand the consistency of promoting the construction of first-class universities, first-class disciplines and the training of first-class talents, firmly establish the principle of the Party’s management of talents, adhere to the "four aspects" and the fundamental task of cultivating people with morality, and promote the deep integration of production, study and research. Double first-class universities should seize opportunities, shoulder responsibilities and call for more talents to emerge, grow and play their roles on the land of China and make greater contributions to the prosperity and rejuvenation of the nation. They should provide replicable and extendable experience for the cultivation of first-class talents, play a leading and exemplary role in the construction of a powerful country in higher education, and build a solid foundation for the realization of the great rejuvenation of the Chinese nation.