In order to understand the research status, hotspot and frontier of Chengdu-Chongqing Economic Circle, and provide analysis reference for further research, this paper selects CNKI database as literature search engine, and uses CiteSpace 5.5.R2 visual analysis software to analyze spatiotemporal features and keyword of Chengdu-Chongqing literatures. Through bibliometrics, this paper mainly analyzes the temporal distribution characteristics such as annual publishing trend, literature citation, and spatial characteristics such as discipline distribution, fund distribution, author and organization distribution. Through the visual analysis of keywords, it draws the co-occurrence map of keywords, time line map, clustering view, time zone view and the distribution map of emergent words to deeply analyze the research hotspots and research frontier. The results of quantitative analysis show that there are a large number of research documents in the field of Chengdu-Chongqing region. However, there is a lack of articles with high recognition in this field, the number of continuous in-depth research documents is small. The cooperation and exchange between authors and research institutions are scarce, and an influential group of authors or institutions has not yet been formed. There are few interdisciplinary research literatures, and the breadth and depth of research in this field need to be developed. In addition, the investment in all aspects of Chengdu-Chongqing area is not enough. Relevant institutions should increase the research investment to improve the research quality. The visual analysis results show that: the high-frequency keywords of relevant research literature of Chengdu-Chongqing Economic Circle tend to be diversified, and Chengdu-Chongqing economic zone is the key word with the highest frequency. According to the time zone chart, the research is divided into five stages, and the literature development of each stage is consistent with the policy background at that time. Emerging words show that in recent years, Chengdu-Chongqing research has been constantly refined. By combing the basic context behind the literature research, this paper points out the economic development process of Cheng-Chongqing region, the problems in the study of Chengdu-Chongqing Economic Circle and its development prospects, which provides a useful reference for further research.