Two monolayer concrete frames with the same reinforcement, KJ1 and KJ2, were designed. KJ1 was designed to simulate low cyclic reversed loading test under weak earthquake. Besides, the fire response test, including temperature rising and lowing, was made by fixing the axial compression ratio of the column. For KJ2, the fire response test at the fixed axial compression ratio was made. The deformation response of the concrete frames in fire was studied. Comparative analysis of the apparent phenomenon, temperature curves, bearing capacity change of the frames were made based on the test results of KJ1 and KJ2. According to the simplified temperature distribution, the ultimate bearing capacity of the column under the high temperature was preliminarily determined. It is illustrated that the calculation results and finally test phenomenon are consistent according to the simplified section.