For multilayer concrete structure, the seismic ability of the ground floor column is very poor, improving the seismic fortification intensity of structure is adopted in this paper, the axial force, shear and moment of beam and column are calculated and analyzed in seven degree and eight degree seismic fortification intensity. Numerical results show that with improving the fortification intensity of the structure, the axial force, shear and moment of beam and column increase and the change of the ground floor is the most prominent. In earthquake the destruction of the structure mainly happens in the ground floor column, so this problem is solved fundamentally with increasing fortification intensity in architectural design.