Under the action of lateral forces and vertical loads, the connection of reinforced concrete slab-column structure will not only transfer significant shear forces, but also unbalanced moment. As to the edge slab-column connection, even if there is no later force, it will also transfer unbalanced moment due to the asymmetry. Currently, most tests and studies focus on interior connections, but there are few tests or studies on edge slab-column connections. A relatively new type of shear reinforcement named shear-stud reinforcement was applied in edge column-slab connections and study on the seismic behavior of these connections was conducted. Tests and finite element analysis of three full-scale reinforced concrete edge slab-column connections subjected to gravity and unbalanced moment were completed in this paper, and main conclusions were as following: the bearing capacity, deformation capacity and seismic behavior of connections reinforced with shear-stud reinforcement are improved; deformation of specimens reinforced with shear-stud reinforcement could meet requirements of current codes; the performance of energy dissipating is as good as the common connections, and has reached the medium ductility level.