The 3D Goodman element is used to simulate segments' cracks in one section of shield tunnel in Guangzhou. Mechanical and deformation characteristics of segment structure responded to varied depth of cracks is analyzed in this paper. Meanwhile, research on coefficient of lateral earth pressure, soil coefficient and ground water level on mechanical and deformation characteristics is carried out. The research result shows that along with the increase of cracks' depth, the tensile stress, pressure stress reach the maximum value while the increment is not too much. However, when the depth equals to the thickness of segment, the reinforcements' tensile stress has increase sharply, even exceeded the allowable value. Moreover, the maximum number of tensile stress, horizontal and vertical convergent value of shield tunnel segment with cracks increase with the reduction of the coefficient of lateral earth pressure and soil coefficient, and increase with the increase of ground water level as well. Specific repair measure has been taken to segments' cracks in this section of shield tunnel based on the conclusions. In general, this section of shield tunnel is stable and safe now, and there is no longer new cracks appeared.