Climate warming has a non-negligible impact on the whole life of building. Accurate assessment of building energy consumption under climate change is important for energy-saving building design and existing building. Climate is the basis for building energy simulation. The global warming will cause the change of building energy consumption. In order to study the impact of climate change on the build energy consumption, the future hourly meteorological parameters are necessary. Based on the latest prediction, the ‘morphing’ methodology is utilized for transforming current Typical Meteorological Year (TMY) into future hourly meteorological file. A high office building is simulated respectively in two different regions Beijing and Guangzhou. The results show that the dry-bulb temperature, moisture content and the solar radiation have an increased trend. In Beijing, the reduction in heating consumption outweighed the increase in summer cooling, which led to the increase of the total energy consumption, but Guangzhou is opposite.