According to the fatigue damage characteristics of galvanized wire, the propagation process is decomposed into 7 stages, including galvanized layer failure, matrix corrosion pit initiation, short crack propagation, long crack propagation and fracture damage stage. Then the expression of time in different stages and the galvanized wire fatigue life expression is established, and the evaluation method of corrosion fatigue is putted forward based on fracture mechanics. Finally through the case analysis of complex factors such as operation under the condition of corrosion environment and stress amplitude, the impact on the wire corrosion fatigue life is analyzed. The results show that the corrosion fatigue life of wire is mainly composed of steel galvanizing layer corrosion, pit development and short crack extension, and in order to accurately assess the corrosion fatigue life of wire, the operating environment and traffic load need to be grasped.