The coupling vibration of space vehicle-bridge of this kind of bridge was analyzed basing on a curved continuous box girder bridge on an ramp.The ANSYS software was used to simulate the beam bridge, and the typical three-axis space vehicle model was selected.The dynamic response and impact of the curved continuous box girder bridge under the braking effect of the vehicle were obtained by the MATLAB program of the highway curve using the modal comprehensive method.And the influence of initial speed, braking position, braking rising time and bridge deck smoothness on dynamic impact coefficient was studied.The results showed that the maximum deflection, deflection and internal force impact coefficient of the main girder do not increase or decrease monotonously with the increase of initial speed, but they are obviously larger than the results when the vehicle runs at the same initial speed and may exceed the standard value.The impact coefficient of deflection and mid-span shear force in front half-span braking is greater than that in the back half-span braking.At the same time, when the braking position of the vehicle is greater than half-span and closer to the fulcrum, the impact coefficient of deflection and internal force is closer to the result of uniform speed braking.With the increase of curvature radius, the impact coefficient of deflection, bending moment and torsion of bridge decreases gradually, while the impact coefficient of shear force increases gradually.In addition, the impact coefficients of deflection, bending moment and torsion curved bridges are larger than those of straight bridges and emergency braking tends to aggravate bridge vibration.