The ribbed prestressed concrete composite wall panel changes the traditional composite wall panel layer into the ribbed layer, and optimizes the concrete configuration of the section to reduce the self-weight of the composite wall panel. Prestressed reinforcement is added to both sides of ribbed prestressed concrete composite wall panel, which can increase the crack resistance of composite wall panel. In order to study the bending performance of the ribbed prestressed concrete composite wall panels, the bending test of 3 specimens under uniform load was carried out, and the mechanical properties and deformation modes of the composite wall panel were analyzed. The calculation formula of flexural bearing capacity was derived through theoretical analysis. The comparative simulation and ribbed plate angle parameter analysis of the composite wall panels were conducted by the finite element software ABAQUS. The results showed that the ribbed prestressed composite wall panel had similar bending behavior to the traditional composite wall panel. The flexural capacity of the ribbed prestressed composite wall panels decreased, but its reduction was less than the self-weight reduction. The application of prestressing can significantly improve the bearing capacity and crack resistance of the composite wall panel. The proposed calculation formula of the bearing capacity and the finite element simulation results of the ribbed prestressed composite wall panels are in good agreement with the experimental results.