In order to reveal the impact of mining activities and ecological restoration measures on soil heavy metal pollution in antimony mining areas, the pollution status and regional characteristics of Sb, As, Pb and Cd in soils of different land properties among smelting area, road nearby ore, mining area and ore tailing area of antimony mine area in Xikuangshan, Hunan were studied, in addition, the ground accumulation index method and the potential ecological risk index method were used to evaluate pollution and ecological risk. It was found that the average contents of Sb, As, Pb and Cd in soil samples in the study area were 3937.72 mg·kg-1, 74.55 mg·kg-1, 254.34 mg·kg-1 and 37.36 mg·kg-1 respectively, and heavy metal compound pollution were serious, which maintaining an upward trend; significant regional characteristics was showed by the heavy metal concentration in soils among each areas because of mining activities such as smelting, mining, transportation and stacking; the content of Sb in soil samples decreased successively in residue-field, wasteland, forestland, sediment, grassland and vegetable-field, which indicated that the method of grassland ecological restoration was an effective method to control soil antimony pollution. The evaluation results of the ground accumulation index method and the potential ecological risk index method showed that Sb and Cd pollution in antimony mining areas are serious, and As and Pb have mild to moderate pollution, and have strong ecological risks comprehensively, of which Sb and Cd are the most important pollution factors.