This study uses a reconstruction project from a provincial boundary (Hunchun) of the National Highway Dana Highway to Dongning section as basis in selecting a representative construction section of earth-rock mixed embankment. Results show the deformation and compaction characteristics of earth-rock embankment under different loose laying depths and different rolling time. In particular, the differential settlement control index is used to determine compaction construction technology of earth-rock embankment with main packing filler of highly-weathered and medium-weathered tuff. Portable falling weight deflectometer (PFWD) is used to detect dynamic elastic modulus (Evd) of earth-rock embankment. The Evd value and differential settlement of earth-rock embankment under each rolling are linear fitted. All correlation coefficients are above 0.86, which indicates that the Evd value has a good linear correlation with the differential settlement. The three-dimensional model of earth-rock embankment built based on finite element theory is used to analyze the dynamic response of embankment under vibration load. The compaction effect and influence depth of the vibratory roller on the roadbed is analyzed. Accordingly, the attenuation rate of the vertical dynamic stress along the depth direction tends to be initially fast and turns slow thereafter. The vibration compaction process of a 32-ton roller can repeatedly reinforce and compact the compaction layer. Variance analysis indicates that the influence of roller vibration frequency on vibration compaction of earth-rock mixed embankment is higher than that of the excitation force.