Compared with the general deep foundation pit engineering, the asymmetric construction of subway deep foundation pit is more difficult and risky.To conduct reasonable and effective risk evaluation of the asymmetric construction of subway deep foundation pit, relying on the deep foundation pit project of a subway in Guangzhou, a risk evaluation index system is established based on enclosure structure, Asymmetric soil pressure of existing stations, foundation pit environment, surrounding environment and site safety management. Fuzzy analytic hierarchy process and multi-level fuzzy comprehensive evaluation method are used to set up an evaluation model for asymmetric construction of deep foundation pit of a subway. According to the quantitative calculation results, the corresponding risk grade of asymmetric construction risk of deep foundation pit in the evaluation set can be obtained. It is consistent with the actual engineering. According to the weight of each index obtained from the evaluation results, corresponding measures can be taken to reduce the risk of the index. The evaluation system and model of the asymmetric construction of deep foundation pit of a subway can be used for reference for similar projects.