In order to explore the aerodynamic force of vehicles at the transition section of embankment and bridge, a 1:50 large-scale embankment-bridge transition section and vehicle experimental model are established in this paper. Two kinds of wind barriers are arranged in the bridge and embankment sections, and multiple pressure measuring points are arranged on the surface of the vehicle model to study the aerodynamic force of vehicles in the embankment-bridge transition section at different wind directions under different windproof measures. The experiment results show that compared with no wind-proof measures, the most unfavorable wind direction angle after the arrangement of the bridge wind barrier will change from -15° to 0°, and the three-component force of the vehicle at the transition section under this wind direction is the largest. After further arrangement of embankment wind barrier, the most unfavorable wind direction angle remains unchanged, but the lateral coefficient and torque coefficient of the vehicle at 0° wind direction angle are greatly reduced. The arrangement of embankment wind barrier can effectively reduce the three-component force of vehicles; the influence of changing the parameters of land wind barrier is not the same in different wind directions. The direction of incoming flow should be fully considered in the arrangement of windbreak measures for embankment-bridge transition section to achieve the optimal effect.