The frame-wall structure is good both in operational performance and mechanical property. In this paper, the shear-wall is considered as a cantilever thin-wall member, and the frame as a multistoreyed shear model. The theory of structural matrix is used to get a series of stiffness matrix formulas of theunsymmetrical framewall structure. The Largrange equation is used to get dynamic equation of the structure in the form of matrix. At last a 43 storeyed model of unsymmetrical frame-wall structure is calculated, the result is close to the test.