An experimental research on the 22 samples of Chongqing sandstone was carried out on the INSTRON press machine. Based on the experimental results, the failure types in the four applied loading paths were analyzed. The deformation and strength properties of Chongqing sandstone were discussed. The quadratic functional relations between the confined pressing and the maximal strain (or the maximal deviated stress) were proposed, which could be applied to the estimating the maximal deformation and strength of Chongqing sandstone under different confined pressing.