A creative test method for post-tensioned prestressed frame is presented in this paper. In the test, the stationary supports at the column base are simulated and the forces at the column base can be tested while the two column bases are not connected with concrete beam. The prestressed secondary moment and the weight-produced moment are established by adjusting the support device at the column base. In this paper, the necessary conditions of the method and the basic process are recommended. It is proved theoretically that the prestressed concrete frame built by this method is equivalent to that used in practice.