Human beings are facing a lot of social, economical and environmental problems, so in 21st century, the sustainable development becomes inevitable choice of human beings. The current situation of municipal solid waste (MSW) and the merits and shortcomings of sanitation landfill, composting, incineration have been expatiated in this paper. If the MSW has been disposed according to the principle of reduction, harmless and resource transformation, the sound base for our country's sustainable development in 21st century will be set.