Yulin River is the major secondary stream of Three Gorges Reservoir Area. According to the requirement of "The Prevention Plan of Water Pollution in Three Gorges Reservoir Area and the Upper Areas (2001-2010)", the water environment pollution in Yulin River valley should be controlled. In this paper the reason of the water pollution is analyzed through investigation and evaluation on the present situation of Yulin River in North Chongqing area, and then a proposal on the prevention and cure measure of water pollution of Yulin River is presented.