Solid phase micro-extraction(SPME) is a new sample pretreatment technique,which developed at the end of 1980s.Because of many its advantages,such as simple and rapid operation,high sensitivity,easy automation,and without using toxic organic solvent,this method has been extensively applied to analyze organic pollutants in environment,food and medicament samples.In this paper,SPME technique and analytical characteristics of organotins were simply introduced,and the application of SPME for organotins analysis in environment samples,such as water,wine,body fluid,sediment and biological samples,were reviewed.According to the recent development of SPME study,it is believed that this technique will be widely used in many fields of chemical analysis.