In this paper, the cause analysis about cracks on the new concrete web poured in multi -span continuous box -girder of a main bridge was introduced. This bridge is a prestressed concrete one with variable cross sections and an 80 -meter main span. When casting reinforced concrete in large volume in box girder during vehicle transport service, the shrinkage cracks in cast -in place reinforced web concrete were formed due to the restriction of old web concrete. Then, the control measure taken on these cracks is discussed.