The heating and air conditioning energy consumption of residential buildings is influenced by the behavior of indoor living personnel.On the basis of research and analysis,two kinds of calculation modes reflecting the behavior of indoor living personnel are estimated.Under two kinds of different calculation modes,by using the building thermal environment simulation Toolkit DeST to simulate the energy consumption calculation for certain residential building in Shanghai,and the simulation results are compared with the research results.The influence of calculation mode on heating and air conditioning energy consumption of residential buildings in Shanghai is analyzed in this paper.In order to obtain the right simulation calculation method correctly reflecting the energy consumption of residential buildings.This method can be used for analysis and evaluation of heating and air conditioning energy consumption of residential buildings in Shanghai,and it can serve as instruction for right energy design of residence building.