The schemes of domestic water supply for a residential quarter of high-rise building are introduced.The energy consumptions of water supply schemes selected are compared and analyzed.The energy saving of the water supply schemes with water tank and variable velocity variable frequency pump are obtained.And demonstrated the domestic water supply system of combination the roof water tank and variable velocity variable frequency pump is good at energy saving.Furthermore,by the comparison of the investment and cost of these schemes in their lives,the best choice of domestic water supply system is gained.