The time-changing analysis model for concrete filled steel tubes was established based on the time-changing concrete model of CEB-FIP MC90, in which the interaction between steel tube and concrete core was considered by the restraint conditions of master and slave nodes. The numerical simulation method was developed for analyzing the whole construction process of high-rise CFST structures. A real structure was taken as numerical example, in which the influence of concrete creep and shrinkage as well as construction process was considered. The results of numerical simulation are compared with those obtained from on-site monitoring. It is shown that the concrete creep and shrinkage as well as construction process have big influence on high-rise CFST structures, which should be taken into account in designs and constructions.