In order to realize the performance target of “no collapse under rare earthquake” based on the seismic design according to structural influencing coefficient, three moment-resisting steel frames have been designed with similar probability of collapse in accordance with Chinese Seismic Code. The structural influencing coefficient of steel frames were determined through the incremental dynamic analysis method, and within equal collapse design rule. This paper proposed a method to define structural influencing coefficient can provide reference for determining the design seismic force of steel frame reasonably.