The aim of this study is to investigate the effect of different inert carrier on the formation of anaerobic granular sludge, which used swine wastewater as a cultivation of anaerobic granular sludge self-made reactor flooding water. The results show that anaerobic reactor which was dosing macroporous type ion exchange resin cultivated granular sludge using 39 d and particle size was 2.50 to 3.00 mm, effluent water COD removal efficiency achieving 80%, methane-producing capacity achieving 9.75 mL CH4·（g VSS·d） -1, comparing with the anaerobic reactor which was dosing polymerization aluminum and fly ash had higher methanogenic activity, comparing with the anaerobic reactor which was not dosing any carrier shorten cultivation time about 20%~45% and granular sludge activity improved 14.00%±0.10%. Referred to Richards model found relationship of methane production and effluent water COD and established mathematical model. Analysis of experimental data and model data deviation was within 0.50%±0.01%.