Through methods of indoor adsorption retardation experiments, established mathematical model of heavy metal pollutants transport, effect of adsorption retardation have been study on the grouting concretion body, so as to reasonable determine the thickness of the wall and design use fixed number of year. The isolation wall made in the clay base grouting consolidation system, has good adsorption retardation, block rate reach upper 98% to NH4-N and phosphorus, block rate reach upper 86.09% to CODCr, BOD5, block rate reach upper 98% to Hg, Pb and other heavy metal ions. Through the infiltration sedimentation and adsorption fixation of clay base slurry material, the retardation capability of it is improved for pollutants of landfill site leachate. Adsorption retardation effect of the isolation wall made in the clay base impervious grouting has timeliness to leachate pollutants for landfill site,to guarantee a certain wall thickness (generally B≥60 cm) can ensures blocking effect to it.