Post-tensioned prestressed concrete beam in tensioning of prestressed reinforcement is based on the symmetry principle to determine the tensioning sequence.Simulation of the tensioning process of a 54m span post-tension concrect beam of a Prestressed Concrete Frame Structure in Fuxin was conducted with the finite element analysis program ADINA. With two different tensioning schemes,the influence of the tensioning sequence on deformation is calculated and then compared with the tensioning one by one in order the tensioning sequence is optimized.