The DeST-H, developed by Tsinghua University, was used to analyze the Heating and cooling energy consumption of the typical design project obtained from the General Dwellings Atlas of Chongqing Ba-Yu New Rural Residential. The whole year energy consumption after opting energy-saving measures was simulated by varying the relevant parameters. Meanwhile, the technical and economic performance were analyzed by taking the cost increment into account which was caused by energy-saving measures. Based on the optimization results, the priority design parameters adapted to residential buildings of new rural development in Chongqing are summarized as follows: exterior wall thermal insulation with 30mm EPS board; the external window of the main function room with Low-e film hollow glass or others with ordinary single 6 mm glass; strengthened ventilation at over-season; indoor temperature in summer is set to 28℃, the heating temperature in winter is set to 16℃; building orientation is north-south.