The s-polynomial transfer function of hollow blocks is obtained from the theoretical frequency characteristics, and the Conduction Transfer Function (CTF) coefficients of the hollow block are derived from the identified s-polynomial transfer function. The dynamic thermal experimental results of a hollow block are used for validating the results by using the CTF coefficients. The comparison shows that the surface temperature of the hollow block calculated by using the CTF coefficients agrees well with the experimental results after the boundary condition tends to be periodically stable. The results further show the identified s-polynomial transfer function as well as the resultant. CTF coefficients can represent accurately the dynamic thermal characteristics of the hollow block. CTF coefficients is an effective approach for analyzing the dynamic thermal characteristic of hollow blocks.