The direct shear tests of clayey soil-concrete interface with six series of shear rates were carried out by using the self-developed large-scale constant normal stiffness pile-soil interface shear apparatus. The effect of shear rate on shear strength of clayey soil-concrete interface was explored in this paper. The test results indicate that excess pore water pressure increases with the increased shear rate. The excess pore water pressure is influenced by both normal stress and shear rate, which is closely related to shear peak strength and shear failure strain of clayey soil-concrete interface. The shear stress-shear strain curves are basically identical at the beginning and then deviate in a certain range, which deviate the more obviously and present significant strain-softening appearing, with higher normal stress and faster shear rate. The decreased magnitude on shear strength of clayey soil-concrete interface increases, and the friction coefficient decreases to 0.1 and the effective adhesive force varies from 0.81 kPa to 5.93 kPa as the shear rate increases from 0.4 mm/min to 5.0 mm/min.