Based on the analysis of ground settlement caused by shield tunneling excavation of a certain section of 4th Line of Wuhan Metro considering tempo-spatial effect of ground settlement, the ground settlement has been divided into five stages as follows:no effect stage, earlier stage, passing stage, tail void stage, passed stage. The distance of each stage between the excavation face and the monitoring section have been suggested. In addition, the ratios of ground settlement in different stages to total settlement have been calculated. The main influence factors of ground settlement in different stages are investigated by introducing time parameter into Mindlin solution. Results show that the friction force and ground loss have more influence on ground settlement before the cutter of the shield machine through monitoring section, and the ground loss has great effect on ground settlement after the cutter through monitoring section. The additional thrust and friction force tend to cause ground-uplifting at the Earlier-stage. Besides, the additional thrust, friction force and grouting pressure may lead to ground resilience during the passed-stage. More importantly, a formula of calculating the real-time ground settlement has been proposed to offer a technical support in engineering construction. The calculated results are in good agreement with the corresponding measured values, indicating that the formula is able to accurately predict the ground settlement in real time.