Based on the vertical compressive static load and pile mechanics tests of 6 large diameter mud-walled bored piles in fully weathered and strongly weathered granite gneiss foundation, including three post-grouting piles in side, the bearing behavior, deformation properties and impact factors are analyzed and the corresponding test data are then compared with the current recommended value of code and survey report. The results show that the Q-s curves of the large-diameter rock-embedded mud-walled bored piles, which are with length-diameter ratio of 25~34 and rock-embedded depths of 5D~8D, present slow type. Compared with no post-grouting piles, the ultimate compressive capacity of post-grouting piles increases by 16.7%~25%, the maximum settlement decreases by 35.1%~65.6%, and the rebound rate increases by 13.1%~82.4%. Besides, the control effect of pile top settlement is remarkable. Under the experimental conditions, the bearing capacity and deformation characteristics of the six test piles are greatly affected by the aspect ratio and the rock-embedded length. Nevertheless, the side resistance in rock-embedded section and side-resistance sharing ratio of the grouting piles is less influenced by the aspect ratio and the rock-embedded depth. The end-resistance sharing ratio of the six test piles and side-resistance sharing ratio of no post-grouting pile is highly affected by the rock-embedded depth.