According to the engineering properties of sandy soil foundation in desert area and the shortcomings of the existing transmission tower foundation, a foundation of plate and ball connected by an anchor cable is developed. By combining the similar model uplift tests and numerical simulations, the displacement of the foundation under different uplift loads is analyzed. Besides, the influence and its rule of buried depth ratio, spherical diameter and column diameter on the ultimate uplift bearing capacity coefficient of the foundation and the radius of main rupture surface of soil surface are studied. The results show that the numerical simulation results are in good agreement with the experimental results. The load-displacement curve presents a three-stage form, which corresponds to the three stages of soil deformation evolution. The ratio of buried depth is of the greatest influence on the ultimate uplift resistance of foundation, and there is a positive correlation between them. The ultimate uplift bearing capacity coefficient increases first and then decreases with increase of burial depth ratio. It is negatively correlated with the sphere diameter and positively correlated with the cement-soil column diameter. The radius of the main rupture surface of soil is negatively correlated with the buried depth ratio, spherical diameter and column diameter.