For efficient reuse of municipal solid waste incinerator bottom ash (MSWIBA), the physical properties and chemical composition test of regenerated powder from MSWIBA, colloidal mortar strength test by substituting cement of different proportion of regenerated powder were carried out. It is shown that the specific density of regenerated powder from MSWIBA is lighter and the particle size is smaller and more uniform than that of cement. The main chemical composition of the regenerated powder are Si, Al and Ca in the form of oxides, which account for about 70% of the total mass, which is similar to the chemical composition of cement, while the content of SiO2 and Al2O3 is little higher, and CaO is little lower. The compressive and flexural mortar strength show a decreasing trend with the increase of the substituting proportion. The strength activity index still exceeds 55% when the replacement proportion reaches 30%, which indicated that recycled micro-powder had certain gel activity. In addition, replace cement with the regenerated powder has slight effect on the early mortar strength than long-term strength, but the early intensity increased slower with the increase of replacement proportion, and long-term strength decreased significantly.