Antibiotics are widely used in various industries, but due to its refractory properties, antibiotic sareenriched in water system and do harm to human health.Many researchers focus on the removal performance of antibiotics in water systems.Bioelectrochemical system (BES) combined with organic substrate biodegradation and electrical signals stimulation effectively accelerates the removal of all kinds of antibiotics in wastewater. Based on previous studies, in this review, the removal performance of antibiotics in BES are summarized. When BES are applied for antibiotic removal, the electroactive bacteria composition and metabolic pathways of electroactive biofilm on electrode surface are expounded. The factors which affecting the removal performance of antibiotics in BES are summarized. And the antibiotic removal efficiency of BES coupled with traditional wastewater treatment technologies are analyzed. Finally, this manuscript summarizes the advantages and disadvantages of BES in antibiotic removal.