Saturated sandy soil ground under earthquake is easy to reach liquefaction state which is of great threat. Soybean-urease induced carbonate precipitation (SICP) cement solidification was conducted using standard sand. Medium dense sand in the relative density of 30%, 40% and 50% was respectively solidified by the cementing fluid once, twice and three times, followed by a dynamic triaxial test under different CSR (ratio of cyclic shear stress to confining pressure). By analyzing dynamic strain, excess pore water pressure and the number of dynamic cycles, the effect of liquefaction resistance of the SICP-method in the treatment of saturated sand was evaluated. The results show that the pore pressure and strain development of the sample both show the characteristics of staged growth. The pore pressure will increase sharply to a certain level at the moment of loading, and then increase at a stable rate with the plastic strain until failed. The SICP-method can effectively enhance the liquefaction resistance of sandy soil and slow down the increasing trend of excess pore water pressure. And the more the number of treatments and the higher the compactness, the better the effect of liquefaction resistance.