Landfill leachate is a complex organic wastewater produced by sanitary landfills, which contains high concentrations of pollutants and is difficult to treat. Anodic oxidation represents a sophisticated technological advancement within the domain of electrochemical oxidation, characterized by high efficiency and low environmental pollution. However, its application is limited by available electrode materials. The Ti₄O₇ electrode is the key to solving the problems of electrode materials for anodic oxidation because of its strong conductivity, corrosion resistance, high oxygen evolution potential and low cost. At present, Ti₄O₇ electrodes have been used to degrade a variety of organic pollutants, including landfill leachate treatment, showing broad application prospects. In this study, a Ti₄O₇ anode reactor was constructed, and two configurations includind were used to Flow-by and Flow-through treat the landfill leachate biochemical effluent. The optimal treatment conditions were determined by considering time, current density, pH, chloride ion concentration and other factors. The experimental results show that the Flow-by mode removes COD up to 77.47% under the optimal conditions, which is better than the 60.56% of the Flow-through mode. Flow-by mode can also change the DOM composition more effectively, with higher initial treatment efficiency, and can mineralized and remove most dissolved organic matter. In treating, the Ti₄O₇ anode reactor has significant advantages in treating landfill leachate.