In order to analyze the influence of over-consolidation state and poisson effect on shear characteristics of sand-pipe pile interface, load transfer model was established on the basis of traditional hyperbolic model, in which the over-consolidation ratio and poisson effect were considered, the reliability of calculation model was verified by existed model test results. Also the factors affecting on limit friction stress were analyzed by an example, results showed that: the ultimate frictional resistance of compressive piles and uplift piles increases approximate linear with the increase of over-consolidation ratio from 1.0 to 3.0, increases range was 83.6% and 92.9% respectively; the ultimate frictional resistance of compressive piles increases linearly with the increase of poisson ratio from 0.1 to 0.3, and the increase range was 3.5%, but the uplift piles decreases linearly with the increase of poisson ratio, and the decrease range was 3.6%; with the pile-soil modulus ratio increases from 300 to 1500, the ultimate frictional resistance of compressive piles decreases about 7.6%, and the uplift piles increases about 9.6%.