An control algorithm with goed robustness has been developed,based on the combination of poletassignment self- tuning control algorithm with robust estimation and control al-gorithms,while the input signal and process parameters are varied on a large scale. The design of controller based on presented algorithm is simple,with good robustness for parameter changes and a strong ability for overcoming determined disturbance.The simulating research results proved the ef-fectiveness of the pole- assienment self-tuning robust control algorithm.