In the domain of HV&AC, there are many problems about pipe network for fluid supply. In order to make analysis on optimized design and project of regulation in operation, some quantitative analysis on hydraulic performances of pipe network should be done. With graph theory and fundamental theory of pipe network for fluid supply. Based on the analysis method of basic loop of pipe network, a convenient, reliable description technique is introduced which could translate pipe system into network graph, and obtains some methods which could get some basic matrix that is needed in pipe network analysis from the graph of pipe network. This article also analyses MATLAB's function, high efficiency in soluting the problems of pipe network analysis and develops relevant program.