For that the characteristics of low voltage power line channel are complicated and variable, how to use low voltage power line to realize reliable and high speed communication has always been the hottest question in power line communication field. This article introduces how to apply MSK to the low voltage power line communication. It analyses the application elements of MSK and structures the model of low voltage power line communication based on MSK. simulation result indicates that MSK modulation technology can satisfy the characteristics that the bandwidth of power line communication channel is narrow and the attenuation to the amplitude of signal is time variable and frequency selected. Also, it makes better use of the spectrum.