The recent works about the accumulation and the harm of persist organic pollutions (POPs) to organisms lied in are widely distributed in lake ecosystem, transferred and biomagnified from prey to predator through pelagic and benthic food web, accumulated in high lipid organ, and increasing concentrations with the increasing of lipid content, age and body length. Until now, the present of POPs in lake ecosystem still has harmful effects to aquatic organism of lakes and can transfers to people through eating fishes from lakes and has some negative effects to human health.