The second step of water storage for Three Gorges Reservoir will be executed in Jue,2003. Because there is still a large quantity of industrial solid waste(ISW) dumped on the reservoir bottom where should be cleaned before water storage and wastes should be disposed. After a full investigation and analyze, the total amount of ISW in the Chongqing reservoir area is about 1.66 million tons. According the principles of safe, economical and reliable, this paper describes the ISW's treatment. The ordinary ISW which is harmless and non toxic after identification should be treated on-site, the ISW that exceeds the national standards should be removed and be disposed in the landfill, and the hazardous waste should be removed for disposition or storage.